Alexander Isak’s goal for Liverpool against Bournemouth on September 20 set the tone for an intense Premier League Gameweek 6, which now brings fresh challenges for managers ahead of crucial fixtures including Arsenal’s home clash with Leeds United and Manchester United’s showdown with Tottenham Hotspur.
After five gameweeks, predicted lineups for this weekend reveal selections that reflect the balancing act managers face with injuries, international fatigue, and the return of European competitions. Arsenal’s formation sticks to a 4-2-3-1, with David Raya starting in goal behind a backline of Timber, Mosquera, Gabriel, and Calafiori. Declan Rice and Lewis-Skelly sit in midfield shielding the defence. Upfront, Bukayo Saka, Martin Odegaard, and Eberechi Eze support the lone striker Gyokeres. Leeds, meanwhile, are expected to field a 4-4-2 with Trafford in goal and a midfield that includes Ampadu, Tanaka, Gudmundsson, and Stach, flanked by Calvert-Lewin and Okafor up front.
Aston Villa’s predicted lineup also follows a 4-2-3-1 shape, with Suzuki guarding the net and a defence led by Wan-Bissaka, Lindelof, Mings, and Ruggeri. Kamara and João Gomes form the double pivot in midfield, while McGinn, Manzambi, and Buendía support Jackson as the striker. Brentford’s setup mirrors this with Kelleher in goal and a midfield anchored by Sangaré and Janelt, pushing Anthony, Yarmolyuk, and Schade ahead of Thiago.
Ipswich Town and Fulham both opt for 4-2-3-1 formations. Ipswich’s Scherpen starts in goal with a back four of O’Shea, Diop, Greaves, and Davis. Lukic and Palacios hold midfield, while Ouattara, Enciso, and Clarke support Emersonn. Fulham’s Leno is expected in goal behind Castagne, Affengruber, Bassey, and Robinson. In midfield, Berge and Charles are set to manage the centre, with Bobb, King, and Iwobi creating chances for Gonzalo García.
Chelsea’s predicted 3-4-2-1 has Martinez in goal and a defence of Fofana, Lacroix, and Colwill. The midfield four includes Neto, Lavia, Henderson, and Chavarría, with Palmer and Welbeck in advanced roles behind striker Rogers. Bournemouth’s line-up is a 4-2-3-1 with Petrovic in goal, Smith, Hill, António Silva, and Truffert defending, and Adams and Cook in midfield. Rayan, Christie, and Tavernier provide support for Evanilson upfront.
Sunderland and Brighton both favour 4-2-3-1 formations. Sunderland’s Roefs is in goal with Mukiele, Danso, Alderete, and Reinildo at the back. Xhaka and Sadiki form the midfield base, while Meunier, Le Fée, and Angulo support striker Isidor. Brighton’s Verbruggen starts in goal, with Kadioglu, Vuskovic, Dunk, and Boscagli in defence. Chema Andrés and Groß are expected in midfield, with Gómez, Ayari, and De Cuyper supporting Kostoulas.
Manchester United’s predicted 4-2-3-1 includes Lammens in goal, a back four of Dalot, Maguire, Martínez, and Shaw, and Tielemans alongside Mainoo in midfield. Bruno Fernandes, Mbeumo, and Rashford form the attacking trio behind Matheus Cunha. Tottenham Hotspur’s lineup mirrors this, with Kinsky in goal, Gray, Van Hecke, Van de Ven, and Robertson in defence. Bentancur and Tonali hold midfield, while Kudus, Gallagher, and Savinho support striker Omar Marmoush.
Crystal Palace and Nottingham Forest both field 3-4-2-1 systems. Palace’s Henderson is in goal with Richards, Lerma, and Canvot defending. Khalaili, Wharton, Timber, and Mitchell form the midfield, with Kamada and Pino supporting Strand Larsen. Nottingham Forest’s Sels starts in goal, backed by Jair, Milenkovic, and Murillo. Muñoz, McAtee, Schlager, and Williams hold midfield, with Gibbs-White and Ndoye playing behind Delap.
Hull City’s 4-3-3 has Tzolakis in goal, with Ajayi, Egan, Mendy, and Coyle at the back. Crooks, Slater, and Giles form the midfield trio, while Belloumi, McBurnie, and Thomas lead the attack. Everton’s predicted 4-2-3-1 sees Pickford in goal, Maitland-Niles, Tarkowski, Branthwaite, and Mykolenko in defence. Armstrong and Garner form the double pivot, with Dibling, Dewsbury-Hall, and Grealish supporting Barry upfront.
Liverpool’s predicted line-up in a 4-2-3-1 has Alisson in goal with Araújo, Jacquet, Van Dijk, and Kerkez forming the back four. Gravenberch and Mac Allister sit in midfield, while Szoboszlai, Wirtz, and Barcola provide support to striker Alexander Isak, who scored against Bournemouth last weekend. Manchester City’s 4-2-3-1 includes Donnarumma in goal, Matheus Nunes, Rúben Dias, Marc Guehi, and Gvardiol defending. Bouaddi and Anderson hold midfield, with Ndiaye, Fernández, and Semenyo behind Erling Haaland.
Coventry City’s 3-4-2-1 predicted lineup has Rushworth in goal, with Mfuni, Thomas, and Pinnock at the back. Van Ewijk, Onyeka, Grimes, and Jay da Silva form midfield, while Rudoni and Mason-Clark support Thomas-Asante. Newcastle United’s 4-2-3-1 includes Hornícek in goal, a defence of Miley, Thiaw, Botman, and Lewis Hall, with González and Steur in midfield. Jacob Murphy, Wissa, and Barnes are expected to back Fernandez-Pardo upfront.
The return of European fixtures next week means these selections could change quickly as managers look to manage player workloads. Injuries and international travel remain factors influencing lineups this weekend, with rotation expected to increase in the coming weeks.
According to Yahoo Sports.