The Green Bay Packers pulled off an upset against the Chicago Bears last week as home underdogs, shaking up NFL Week 6 odds ahead of a slate featuring six divisional matchups, including the Houston Texans facing the Jacksonville Jaguars in London.
Week 5 saw underdogs flexing their muscles, with the Packers’ win over the Bears and the San Francisco 49ers’ victory at Seattle standing out. The Tampa Bay Buccaneers also pulled off a surprise by beating the Dallas Cowboys on Thursday night with rookie undrafted quarterback Jalon Daniels starting. These results have influenced the betting lines heading into the next round of games.
Seattle, reeling from the 49ers loss at home, travels to Denver in Week 6. The Seahawks opened as 1.5-point favorites, but the line has shifted to the Broncos favored by three points. Denver has a 2-0 record against the spread (ATS) at home this season and was 3-0 ATS as a home underdog last year. Seattle is 1-1 ATS as a road favorite this season.
The Jaguars, coming off a narrow win over the Eagles in London but failing to cover the spread, will stay in England for their game against the Texans, who must make the international trip later in the week. Jacksonville sits at 3-2 ATS, while Houston, fresh off their first win of the season against the Tennessee Titans, earned their first ATS victory as well. The total points line is at an under 43.5, reflecting a history of low-scoring affairs between these AFC South rivals.
Cleveland, after losing on the road to the Jets, will host the Baltimore Ravens as 3.5-point home underdogs. The Browns are 3-2 both straight up and ATS this season and have been perfect ATS at home so far. Baltimore is coming off a road win in Atlanta. The status of Lamar Jackson, who did not play in Week 5, could affect betting lines once confirmed.
Chicago’s fortunes have shifted since opening as 1.5-point road favorites against Atlanta. Now, the Falcons are favored by 1.5 points at home. The Bears lost last week as road favorites to Green Bay, leading to a quarterback change from Tyson Bagent to Case Keenum. If Caleb Williams suits up for the Falcons, the odds may swing again. Michael Penix Jr. left Baltimore’s game with a rib injury, and if he cannot play in Week 6, that would impact the lines, especially with Tua Tagovailoa’s overtime interception in the same match.
The Carolina Panthers, coming off their bye week, will face the Philadelphia Eagles, who played in London last week. The Eagles are narrow 1.5-point favorites despite several injury concerns, including DeVonta Smith and Saquon Barkley. Panthers coach Dave Canales has a 3-3 ATS record when his team has a rest advantage, while Eagles coach Nick Sirianni’s teams are 9-11 ATS when facing a rest disadvantage.
New York Giants host the New Orleans Saints, with the Giants favored by 1.5 points. The Saints have lost three straight home games, including a recent defeat to Minnesota. The Giants are unbeaten ATS at home this season (3-0), while the Saints have a perfect 2-0 ATS record on the road.
New England is a seven-point favorite against the Jets after back-to-back wins, including a 45-point offensive outburst over the Raiders. The Patriots are 3-2 overall and 3-1-1 ATS this season, with a flawless 2-0 ATS record at Gillette Stadium. The Jets, riding a win over Cleveland, sit at 3-1-1 ATS but have been mixed on the road (1-1-1 ATS).
The Indianapolis Colts have moved from a 6.5 to a 7-point favorite against the Tennessee Titans, with both coming off Week 5 losses. The Colts fell to the Steelers, while the Titans lost to the Texans. At home, the Colts are 1-1 ATS, and the Titans hold a 1-1 ATS record on the road.
Tampa Bay faces the Pittsburgh Steelers after a short rest. Despite that, the Steelers are favored by three points at Tampa Bay. The Buccaneers have struggled against the spread this season, especially at home (0-3 ATS), while Pittsburgh has yet to record an ATS road win and is 0-1 ATS as a road favorite.
The Los Angeles Rams, who still have a Week 5 game pending against Buffalo, opened Week 6 as the biggest favorites. They are laying 12.5 points at home to the Arizona Cardinals, who recently lost 45-21 to the Detroit Lions. Arizona is 2-3 ATS overall and 2-1 ATS on the road, while the Rams are 1-1 ATS at home and 2-2 ATS in total this season.
Cincinnati, Detroit, Miami, and Minnesota remain on bye in Week 6, narrowing the field as teams continue to jockey for position in what has been a competitive and unpredictable NFL season so far.
According to CBS.
