The Arizona Cardinals are facing a Detroit Lions defense that recently allowed 445 yards to the Carolina Panthers, setting the stage for a high-scoring affair in Week 5. Tight end Trey McBride, who ranks third in the NFL with 33 receptions this season but hasn’t scored in two weeks, is a strong anytime touchdown candidate. Detroit’s defense, coordinated by Kelvin Sheppard, currently sits at the bottom of the league, which increases the chances of McBride breaking the end zone drought.
Meanwhile, Christian McCaffrey of the San Francisco 49ers is listed at -130 odds to score a touchdown against the Seattle Seahawks. This is a surprising price given Seattle’s status as the NFL’s top-ranked defense. McCaffrey has found the end zone four times in the last three games but has yet to score a receiving touchdown this season. With just one more receiving touchdown, he would surpass Marshall Faulk for the most receiving touchdowns by a running back in NFL history, currently at 36.
Dalton Schultz, the Houston Texans tight end, is another player to watch. Schultz exploded in Week 2 with 12 catches for 140 yards against the Cincinnati Bengals, but aside from that game, his production has been modest. He has 21 receptions for 214 yards on 27 targets, tied for fourth-most among tight ends. Schultz is a preferred red-zone target for quarterback C.J. Stroud and could find the end zone this Sunday against the Tennessee Titans.
The Pittsburgh Steelers’ rookie wide receiver Germie Bernard is in line for increased opportunities. Michael Pittman Jr. was ruled out with a foot injury, and Bernard’s snaps are expected to rise after playing just 40 percent of offensive snaps last week against the Cleveland Browns. When Pittman missed Week 2, Bernard saw eight targets and caught four passes for 35 yards. The Indianapolis Colts, who just returned from London and rank as the NFL’s fourth-worst passing defense, provide a promising matchup for Bernard, whose anytime touchdown odds are currently +400.
Denver Broncos running back RJ Harvey, second in the NFL for yards after catch with 193, is still seeking his first touchdown of the 2026 season. He averages over six receptions per game and showed last year he can score both on the ground and through the air, becoming the fifth rookie in NFL history to record at least five rushing and five receiving touchdowns in a single season. With Sean Payton resuming play-calling duties, Harvey could find the end zone either rushing or receiving in the upcoming game.
These five players offer a blend of reliable targets and value picks for fans interested in anytime touchdown bets during NFL Week 5. McBride’s opportunity against a struggling defense, McCaffrey’s chase of an all-time receiving mark, Schultz’s role in Houston’s red zone, Bernard’s expanded role due to injury, and Harvey’s dual-threat potential with a new play caller all present intriguing angles this Sunday.
According to CBS.
